How Smoking, Vaping, and Medications Turn Your Teeth Yellow
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You already know smoking is bad for your lungs—but did you know it’s just as harmful to your teeth? Smoking, vaping, and medications that stain teeth are more common than you might think, and they can also contribute to enamel damage.
In this blog, we’ll look at how routine behaviors, that are frequently employed to reduce stress or treat medical issues, might subtly deteriorate your smile and oral health
📑 Table of Contents
How Smoking or Vaping Stains Teeth
Smoking

According to the American Dental Association (ADA), a variety of oral health conditions can result from tobacco and nicotine products, such as cigarettes, smokeless tobacco, dissolvable forms, cigars, pipes, and e-cigarettes.
Vaping

Aside from gum issues, vaping can harm oral health and lead to visible tooth stains. Even without tar, vaping still involves nicotine, which can decrease the blood flow to the gums. This can contribute to gum disease, dry mouth, and tooth discoloration.
Plus, the flavoring agents used in vape, combined with the enamel-weakening effects of nicotine, will make it faster for staining chemicals to seep deeper into your teeth. Hence, the development of extrinsic stains.
Wanna know if the stain on your teeth is surface-level or deep-seated? Read: Tooth Stain Colors Explained: What Yellow, Gray, and Purple Teeth Really Mean
Medications that Stain Teeth
Even if they seem harmless, certain prescription drugs can still stain your teeth over time. Here’s 5 medications that can change your tooth color:
Antibiotics
Common antibiotics, like Tetracycline and Doxycycline, have been shown to discolor developing teeth. For this reason, they are usually avoided during pregnancy and children younger than eight years old to avoid permanent tooth discoloration.
Antihistamines
The usual antihistamines used to counter allergies, such as Loratadine and Diphenhydramine, can decrease salivary flow, resulting in dry mouth. Tooth decay, fungal infections, and possibly tooth discoloration have a higher chance of developing due to dry mouth.
Blood Pressure Medications
Well-known blood pressure medications, such as Amlodipine, Propranolol, and Lisinopril, can also induce dry mouth, a side effect that may indirectly exacerbate tooth decay and discoloration.
Liquid Iron Supplements
Iron supplements, especially in liquid form, can discolor teeth. If unattended, they can cause black, gray, deep yellow, or brown discoloration.
Mouthwashes with Chlorhexidine
Long-term usage of mouthwashes containing chlorhexidine can cause brown discoloration on teeth. In certain cases, it may even increase plaque accumulation instead of decreasing it.
Bonus: Betel Nut
According to WebMD, betel nut is frequently used in several cultures for its supposed therapeutic benefits, which include helping with digestion, schizophrenia, and glaucoma. These assertions, however, are not well supported by scientific data. There’s no denying that frequent chewing of betel nut can cause deep reddish-brown discoloration on teeth and gums, which may also be a contributing factor to long-term oral health problems.
Want to learn more about stain-causing foods? Read: 12 Surprising Foods and Drinks That Stain Your Teeth — And What to Do
Unsure How to Whiten Discolored Teeth by Tobacco or Pharmaceutical Use?
Although it may be annoying, tooth discoloration caused by smoking, vaping, or certain medications doesn’t have to be permanent. In fact, there are several ways to undo it.
Awareness is the first step. Action comes next. Your smile can be kept bright—or restored if stains have already formed—by avoiding harmful habits, practicing good oral hygiene, and using the appropriate whitening solutions.
If you’re looking for the best whitening kit for smokers, or just want a convenient way to whiten stained teeth, try ClearClub’s Whitening Kit or Cleaning + Whitening Foam. Both are gentle on enamel, tough on stains, and safe for sensitive teeth (and your budget).
Wondering how to undo the damage from smoking or meds? Check out: 10 Proven Teeth Whitening Tips for Smokers and Medication Users
Want a closer look? Just click the images to preview what we offer!
Frequently Asked Questions
❓ Can I prevent yellowing if I smoke or vape?
Yes! You can still prevent yellowing even if you smoke or vape. The key is to be mindful of your habits—limit exposure, maintain good oral hygiene, and use gentle whitening treatments to reduce staining.
❓ Are there safe whitening options for sensitive teeth?
Certainly. Brands like ClearClub offer whitening kits specifically designed for sensitive teeth, available in three strengths (10%, 20%, and 30%). We also have a 2-in-1 Cleaning + Whitening Foam that reduces bacterial growth while wearing a night guard and helps whiten your teeth safely.
❓ How do smoking, vaping, and medications stain teeth?
In simple terms, smoking and vaping stain teeth because of chemicals like nicotine and propylene glycol. These substances can dry out your mouth and contribute to enamel erosion, making teeth more prone to stains. Tar, flavorings, and certain medications can also leave discoloration and create yellow or brown hues on your teeth.
Looking for something else? Check our full FAQ section.